Mitochondrial Release of Pro-apoptotic Proteins
نویسندگان
چکیده
منابع مشابه
Mitochondrial release of pro-apoptotic proteins: electrostatic interactions can hold cytochrome c but not Smac/DIABLO to mitochondrial membranes.
A key step in the initiation of apoptosis is the release from the mitochondrial intermembrane space of cytochrome c and other pro-apoptotic proteins such as Smac/DIABLO, Omi/HtrA2, apoptosis-inducing factor (AIF), and endonuclease G (EndoG). Discrepancies have arisen, however, as to whether all these proteins are released in different systems. Our results suggest that failure to observe cytochr...
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School of Medical Science, Griffith University, Southport 4222, Qld, Australia, Department of Chemistry, University of Otago, Dunedin 9016, New Zealand, Eskitis Institute for Cell and Molecular Therapies, Griffith University, Nathan 4111, Qld, Australia, Institute of Biotechnology, Academy of Sciences of the Czech Republic, Prague 14220, Czech Republic, Department of Chemistry and Physics, Loui...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2005
ISSN: 0021-9258
DOI: 10.1074/jbc.m411106200